|
I. CBS: core criteria
|
|
Inclusion criteria (1 plus 2)
|
| |
1. Progressive course
|
| |
2. At least three of the following:
|
| | |
a. Parkinsonism (bradykinesia or rigidity)
|
| | |
b. Dystonia
|
| | |
c. Myoclonus
|
| | |
d. Impairment in voluntary limb control (alien limb)
|
| | |
e. Cortical sensory deficit (symmetric/asymmetric)
|
|
Exclusion criteria (all must be negative)
|
| | |
a. Visual hallucinations
|
| | |
b. REM sleep behavior disorder
|
| | |
c. Cerebellar ataxia
|
| | |
d. Prominent autonomic dysfunction
|
| | |
e. Fluctuations in alertness
|
| | |
f. Prominent rest tremor
|
|
II. CBS- frontal variant:
|
|
Inclusion criteria (meets core plus one of the following must be positive)
|
| |
1. Agrammatism, non-fluent speech or motor speech deficits
|
| |
2. Apathy, disinhibition or loss of empathy
|
| |
3. Apraxia primarily affecting lower extremities
|
| |
4. Prominent executive dysfunction greater than memory or visuospatial impairment
|
|
III. CBS- temporoparietal variant:
|
|
Inclusion criteria (meets core plus one of the following must be positive)
|
| |
1. Logopenic aphasia [16]
|
| |
2. Elements of Gerstmann or Balint syndrome
|
| |
3. Episodic memory or visuospatial impairment greater than executive dysfunction
|
