Table 2 Small molecule BACE1 inhibitors in clinical trials
From: BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
Company | Drug | Phase |
|---|---|---|
AstraZeneca/Lilly | AZD3293 | Phase 2/3 |
CoMentis | CTS-21166 | Phase 1 |
Eisai/Biogen Idec | E2609 | Phase 2 |
High Point | HPP854 | Phase 1 |
Janssen/Shionogi | - - - - - - | Phase 1 |
Lilly | LY2886721 | Phase 2* |
Merck | MK-8931 | Phase 2/3 |
Novartis | - - - - - - | Phase 1 |
Pfizer | PF-05297909 | Phase 1 |
Roche | RG7129 | Phase 1** |
Takeda | TAK-070 | Phase 1 |
Vitae/Boehringer Ingelheim | VTP-37948 | Phase 1 |