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Figure 6 | Alzheimer's Research & Therapy

Figure 6

From: Long-term donepezil use for dementia with Lewy bodies: results from an open-label extension of Phase III trial

Figure 6

Mean NPI-2 change in subgroups of improved and less improved by 5 mg (FAS, DON5-DON10 group). NPI, Neuropsychiatric Inventory; FAS, full analysis set; LOCF, last observation carried forward. (a)The behaviorally improved by 5 mg is defined as a patient with 30% or more improvement in NPI-2 score at Week 24, and the less-improved as a patient with less than 30% improvement. (b)Treatment with 10 mg started at Week 24 (dose decrease to 5 mg was allowed). *P < 0.05 (paired t test versus Week 24).

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