From: Elevated cerebrovascular resistance index is associated with cognitive dysfunction in the very-old
Young-old (60 to 75) | Very-old (80+) | P | |
---|---|---|---|
Number | 38 | 20 | |
Age (years) | 69.1 (3.9) | 84.8 (4.0) | <.001 |
Gender (M/F) (number) | 14/24 | 9/11 | .55 |
Education (years) | 15.9 (1.9) | 15.7 (3.0) | .69 |
APOE (ε4-negative/ε4-positive) (number) | 21/15 | 14/6 | .39 |
Systolic BP | 125.8 (14.2) | 136.2 (17.8) | <.05 |
Diastolic BP | 74.9 (7.7) | 77.8 (11.7) | .26 |
Mean arterial pressure | 91.9 (8.6) | 97.3 (13.0) | .06 |
Pulse pressure | 50.9 (12.4) | 58.4 (11.3) | <.05 |
Anti-hyperintensive medication use (number currently prescribed medication/number not currently prescribed medication) | 17/21 | 14/6 | .07 |
CVLT-II Long delay free recall z-score | 0.3 | 0.6 | .42 |
D-KEFS Verbal fluency (letter) ss | 12.4 | 13.2 | .46 |
D-KEFS Trail making test switching ss | 12.3 | 12.1 | .82 |