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Table 4 Prevalence by age group and type of classification (clinical and pathological) in the Spanish population

From: Fitting the epidemiology and neuropathology of the early stages of Alzheimer’s disease to prevent dementia

   Clinical classification a Pathological classification b
Age group Population Preclinical Prodromal Dementia Thal1 Thal2 Thal3
Number        
40 to 44 2,981,900 252,700 800 0 253,500 16,900 9,400
45 to 49 3,530,900 388,400 4,900 0 393,300 47,200 19,800
50 to 54 3,109,400 431,800 9,400 1,100 442,300 93,600 31,600
55 to 59 2,620,100 517,600 19,400 3,200 540,200 172,400 49,900
60 to 64 2,438,200 739,200 43,500 9,200 791,900 336,900 82,400
65 to 69 2,091,000 929,800 79,800 17,800 1,027,400 461,000 120,900
70 to 74 1,705,800 817,900 148,900 31,300 998,100 583,200 178,600
75 to 79 1,653,700 699,100 291,800 58,200 1,049,100 814,400 266,400
80 to 84 1,218,300 329,500 418,600 90,500 838,600 709,500 277,300
85 to 89 659,500 67,200 330,800 90,400 488,400 416,600 195,600
90 to 94 215,100 14,100 97,300 52,200 163,600 136,000 74,700
>95 38,400 2,700 9,100 16,400 28,200 22,800 14,100
Total >40 22,262,300 5,190,000 1,454,300 370,300 7,014,600 3,810,500 1,320,700
Total >60 10,020,000 3,599,500 1,419,800 366,000 5,385,300 3,480,400 1,210,000
Percentage        
40 to 44 100.0 8.5 0.0 0.0 8.5 0.6 0.3
45 to 49 100.0 11.0 0.1 0.0 11.1 1.3 0.6
50 to 54 100.0 13.9 0.3 0.0 14.2 3.0 1.0
55 to 59 100.0 19.8 0.7 0.1 20.6 6.6 1.9
60 to 64 100.0 30.3 1.8 0.4 32.5 13.8 3.4
65 to 69 100.0 44.5 3.8 0.9 49.1 22.0 5.8
70 to 74 100.0 47.9 8.7 1.8 58.5 34.2 10.5
75 to 79 100.0 42.3 17.6 3.5 63.4 49.2 16.1
80 to 84 100.0 27.0 34.4 7.4 68.8 58.2 22.8
85 to 89 100.0 10.2 50.2 13.7 74.1 63.2 29.7
90 to 94 100.0 6.6 45.2 24.3 76.1 63.2 34.7
>95 100.0 7.0 23.7 42.7 73.4 59.4 36.7
Total >40 100.0 23.3 6.5 1.7 31.5 17.1 5.9
Total >60 100.0 35.9 14.2 3.7 53.7 34.7 12.1
  1. aData for clinical stages are not aggregated. bData for pathological classification prevalence are aggregated.