Correlation between pSer129 α-syn and Braak stage in combined PD (n = 35) and DLB (n = 10) patients. Each point represents a separate case. The best-fit linear regression (solid lines) and 95% confidence intervals (interrupted lines) are superimposed. Only significant P-values (and associated correlation coefficients) are shown in the figure. Insoluble pSer129 α-syn level correlated positively with Braak stage in the midfrontal cortex. Soluble pSer129 α-syn level correlated negatively with Braak stage in the cingulate cortex. DLB, dementia wth Lewy bodes; PD, Parkinson’s disease; pSer129 α-syn, alpha-synuclein phosphorylated at serine 129.