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Table 5 Areas of relative hypoperfusion on SPECT when CBS compared to their respective control groups

From: Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography

Anatomical locus (Brodmann area)

Talairach coordinates

Number of voxels

SPM t-score (P-value)

x

y

z

  

CBS versus controls (FWE-corr)

     

Right middle frontal gyrus (6)

50

8

42

236

5.4 (P =0.003)

Left superior frontal gyrus (6)

−18

9

70

99

5.4 (P =0.005)

CBS versus controls (FDR-corr)

     

Right middle frontal gyrus (6)

50

8

42

1791

5.4 (P =0.005)

Right superior frontal gyrus (6)

6

7

70

 

4.7 (P =0.007)

Right sub-gyrus (6)

30

−1

55

 

4.0 (P =0.014)

Left superior frontal gyrus (6)

−18

9

70

850

5.4 (P =0.005)

Left superior frontal gyrus (6)

0

−2

68

 

3.5 (P =0.020)

Left middle frontal gyrus (6)

−26

−1

50

 

3.6 (P =0.019)

Left precentral gyrus (9)

−34

9

31

203

4.4 (P =0.009)

Left precuneus (7)

−2

−57

62

655

4.4 (P =0.009)

Right precuneus (7)

4

−53

65

 

4.4 (P =0.010)

Left postcentral gyrus (7)

−4

−51

67

 

3.7 (P =0.017)

Left superior parietal lobule (7)

−34

−53

60

834

4.1 (P =0.013)

Left superior parietal lobule (7)

−32

−46

47

 

3.8 (P =0.017)

Left postcentral gyrus (2)

−30

−37

70

 

4.0 (P =0.015)

Right postcentral gyrus (2)

34

−35

68

213

4.1 (P =0.013)

Right postcentral gyrus (2)

48

−27

40

163

3.9 (P =0.015)

Right inferior frontal gyrus (47)

44

17

−3

96

3.8 (P =0.016)

Right superior frontal gyrus (10)

32

57

23

31

3.8 (P =0.017)

Right superior parietal lobule (7)

32

−59

58

67

3.7 (P =0.017)

  1. CBS, corticobasal syndrome; FDR-corr, corrected for False Discovery Rate; FWE-corr, corrected for Family-Wise Error; SPECT, single-photon emission computed tomography; SPM, Statistical Parametric Mapping.