Skip to main content

Table 3 Efficacy parameters for prediction of clinical diagnosis 1 year post scan: Mini-Mental State Examination ( n = 92)

From: Association between Hoehn and Yahr, Mini-Mental State Examination, age, and clinical syndrome predominance and diagnostic effectiveness of ioflupane I 123 injection (DaTSCANTM) in subjects with clinically uncertain parkinsonian syndromes

Subjects with CUPS Clinical diagnosis at 1 year post-scan
Subgroup: MMSE <29 Subgroup: MMSE ≥29
PS Non-PS Total PS Non-PS Total
Abnormal ioflupane [ 123 I] images a 19 1 20 27 1 28
Normal ioflupane [ 123 I] images 1 16 17 2 25 27
Total 20 17 37 29 26 55
Statistic Result Exact 95% CI   Result Exact 95% CI P value/analysis method b
Sensitivity c 0.9500 (0.7513, 0.9987)   0.9310 (0.7723, 0.9915) 1.0000
Specificity d 0.9412 (0.7131, 0.9985)   0.9615 (0.8036, 0.9990) 1.0000
Accuracy 0.9459 (0.8181, 0.9934)   0.9455 (0.8488, 0.9886) 1.0000
Positive predictive value 0.9500 (0.7513, 0.9987)   0.9643 (0.8165, 0.9991) 1.0000
Negative predictive value 0.9412 (0.7131, 0.9985)   0.9259 (0.7571, 0.9909) 1.0000
  1. CI, confidence interval; CUPS, clinically uncertain parkinsonian syndrome; MMSE, Mini-Mental State Examination; PS, parkinsonian syndrome. aAbnormal imaging types 1, 2 and 3.
  2. b P value is based on Fisher’s exact test. cSensitivity is equivalent to positive percent agreement. dSpecificity is equivalent to negative percent agreement.