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Table 3 Comorbidity profile of patients with dementia with Lewy bodies ( n = 634) versus Alzheimer’s disease patients ( n = 9,161) within different subgroups regarding gender, cognitive level at the time of diagnosis and living place using the chapters of the International Statistical Classification of Diseases and Related Health Problems, 10th Revision

From: Comorbidity profile in dementia with Lewy bodies versus Alzheimer’s disease: a linkage study between the Swedish Dementia Registry and the Swedish National Patient Registry

Title

Gender

DLB (%)

AD (%)

Pvalue

Cognition

DLB (%)

AD (%)

Pvalue

Living place

DLB (%)

AD (%)

Pvalue

Certain infectious and parasitic diseases

Male

14.9

12.5

0.183

MMSE≥22

16.3

11.2

0.005

Own house

14.3

11.4

0.038

Female

11.9

11.1

0.703

MMSE≤22

11.9

12.2

0.855

Nursing home

9.3

15.0

0.188

Neoplasms

Male

35.6

33.8

0.494

MMSE≥22

32.8

31.6

0.652

Own house

32.4

30.1

0.259

Female

26.6

27.7

0.701

MMSE≤22

31.9

27.9

0.169

Nursing home

29.3

25.4

0.467

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Male

5.2

4.8

0.687

MMSE≥22

3.6

4.5

0.447

Own house

4.7

4.6

0.967

Female

3.6

4.7

0.403

MMSE≤22

5.9

4.8

0.414

Nursing home

4.0

6.8

0.457

Endocrine, nutritional and metabolic diseases

Male

12.8

10.9

0.262

MMSE≥22

10.5

11.7

0.526

Own house

12.3

11.8

0.700

Female

11.9

12.4

0.819

MMSE≤22

15.9

11.8

0.046

Nursing home

13.3

13.5

0.973

Mental and behavioral disorders

Male

67.3

37.4

<0.001

MMSE≥22

65.7

40.8

<0.001

Own house

65.5

38.8

<0.001

Female

64.3

39.3

<0.001

MMSE≤22

66.7

36.0

<0.001

Nursing home

70.7

36.5

<0.001

Diseases of the nervous system

Male

91.4

72.8

<0.001

MMSE≥22

89.5

75.5

<0.001

Own house

88.7

72.2

<0.001

Female

82.9

70.1

<0.001

MMSE≤22

86.3

66.8

<0.001

Nursing home

82.7

52.3

<0.001

Diseases of the eye and adnexa

Male

56.5

44.2

<0.001

MMSE≥22

60.2

49.0

<0.001

Own house

58.3

47.7

<0.001

Female

59.9

49.9

0.002

MMSE≤22

55.6

47.0

0.007

Nursing home

54.7

52.0

0.660

Diseases of the ear and mastoid process

Male

15.4

17.2

0.383

MMSE≥22

17.5

17.1

0.857

Own house

15.7

16.2

0.790

Female

14.7

15.3

0.794

MMSE≤22

14.1

14.6

0.819

Nursing home

10.7

12.9

0.588

Diseases of the circulatory system

Male

45.8

43.5

0.391

MMSE≥22

43.7

40.8

0.296

Own house

46.3

40.2

0.005

Female

46.8

38.6

0.009

MMSE≤22

49.6

39.1

0.001

Nursing home

45.3

41.2

0.499

Diseases of the respiratory system

Male

27.7

20.5

0.001

MMSE≥22

22.0

17.6

0.043

Own house

22.9

18.0

0.004

Female

15.9

16.9

0.677

MMSE≤22

24.4

18.6

0.018

Nursing home

24.0

20.1

0.438

Diseases of the digestive system

Male

41.6

37.0

0.079

MMSE≥22

36.7

34.3

0.357

Own house

37.7

32.7

0.013

Female

31.0

29.9

0.721

MMSE≤22

38.9

30.3

0.003

Nursing home

34.7

27.9

0.229

Diseases of the skin and subcutaneous tissue

Male

24.3

20.2

0.057

MMSE≥22

25.3

22.5

0.230

Own house

24.7

21.1

0.043

Female

24.6

21.3

0.217

MMSE≤22

24.1

19.3

0.056

Nursing home

22.7

18.6

0.397

Diseases of the musculoskeletal system and connective tissue

Male

39.8

36.1

0.157

MMSE≥22

41.3

42.9

0.555

Own house

42.9

41.0

0.371

Female

48.0

43.2

0.132

MMSE≤22

45.6

38.5

0.022

Nursing home

44.0

37.5

0.280

Diseases of the genitourinary system

Male

36.4

32.1

0.093

MMSE≥22

38.0

33.6

0.108

Own house

38.3

32.6

0.005

Female

37.3

32.8

0.138

MMSE≤22

35.6

31.1

0.132

Nursing home

25.3

32.6

0.205

Pregnancy, childbirth and the puerperium

Male

MMSE≥22

0.3

0

0.062

Own house

0.2

0

0.061

Female

0.4

0

0.117

MMSE≤22

0

0.1

1

Nursing home

0

0.4

1

Certain conditions originating in the perinatal period

Male

0

0

MMSE≥22

0

0

Own house

0

0

Female

0

0

MMSE≤22

0

0

Nursing home

0

0

Congenital malformations, deformations and chromosomal abnormalities

Male

1.0

0.6

0.300

MMSE≥22

0.9

0.6

0.464

Own house

0.7

0.5

0.545

Female

0.4

0.6

1

MMSE≤22

0.7

0.4

0.349

Nursing home

1.3

2.1

1

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Male

72.8

66.9

0.020

MMSE≥22

74.1

67.2

0.010

Own house

72.3

64.5

<0.001

Female

72.2

63.0

0.003

MMSE≤22

71.5

61.3

0.001

Nursing home

74.7

62.7

0.043

Injury, poisoning and certain other consequences of external causes

Male

50.8

45.1

0.034

MMSE≥22

59.6

49.2

<0.001

Own house

58.3

50.2

<0.001

Female

69.4

54.3

<0.001

MMSE≤22

56.7

53.5

0.312

Nursing home

57.3

64.8

0.206

External causes of morbidity and mortality

Male

0

0

MMSE≥22

0

0

Own house

0

0

Female

0

0

MMSE≤22

0

0

Nursing home

0

0

Factors influencing health status and contact with health services

Male

81.4

73.0

<0.001

MMSE≥22

84.3

76.8

0.001

Own house

83.2

73.8

<0.001

Female

84.1

73.5

<0.001

MMSE≤22

81.1

69.8

<0.001

Nursing home

77.3

65.8

0.047

  1. Statistically significant differences (P≤0.05) in bold. Univariate comparisons were performed using either the chi-square or Fisher’s exact test wherever appropriate. AD, Alzheimer’s disease; DLB, dementia with Lewy bodies; MMSE, Mini-Mental State Examination.