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Table 2 Comorbidity profile of the patients with dementia with Lewy bodies versus Alzheimer’s disease patients based on the chapters of the International Statistical Classification of Diseases and Related Health Problems, 10th Revision

From: Comorbidity profile in dementia with Lewy bodies versus Alzheimer’s disease: a linkage study between the Swedish Dementia Registry and the Swedish National Patient Registry

Chapter Blocks Title DLB AD Unadjusted Pvaluea Adjusted Pvalueb
(n=634) (n=9,161) OR (95%CI) OR (95%CI)
I A00 to B99 Certain infectious and parasitic diseases 87 (13.7) 1,064 (11.6) 1.21 (0.96 to 1.53) 0.111 1.25 (0.98 to 1.59) 0.069
II C00 to D48 Neoplasms 203 (32.0) 2,733 (29.8) 1.11 (0.93 to 1.32) 0.245 1.06 (0.88 to 1.27) 0.541
III D50 to D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism 29 (4.6) 433 (4.7) 0.97 (0.66 to 1.42) 0.861 1.01 (0.68 to 1.49) 0.976
IV E00 to E90 Endocrine, nutritional and metabolic diseases 79 (12.5) 1,088 (11.9) 1.06 (0.83 to 1.35) 0.661 1.16 (0.90 to 1.49) 0.239
V F00 to F99 Mental and behavioral disorders 419 (66.1) 3,543 (38.7) 3.09 (2.61 to 3.66) <0.001 3.14 (2.63 to 3.75) <0.001
VI G00 to G99 Diseases of the nervous system 558 (88.0) 6,508 (71.0) 2.99 (2.34 to 3.82) <0.001 2.78 (2.15 to 3.58) <0.001
VII H00 to H59 Diseases of the eye and adnexa 367 (57.9) 4,390 (47.9) 1.49 (1.27 to 1.76) <0.001 1.69 (1.42 to 2.01) <0.001
VIII H60 to H95 Diseases of the ear and mastoid process 96 (15.1) 1,462 (16.0) 0.94 (0.75 to 1.18) 0.586 0.97 (0.77 to 1.22) 0.810
IX I00 to I99 Diseases of the circulatory system 293 (46.2) 3,693 (40.3) 1.27 (1.08 to 1.49) 0.003 1.29 (1.08 to 1.52) 0.004
X J00 to J99 Diseases of the respiratory system 146 (23.0) 1,663 (18.2) 1.35 (1.11 to 1.63) 0.002 1.30 (1.06 to 1.59) 0.010
XI K00 to K93 Diseases of the digestive system 237 (37.4) 2,966 (32.4) 1.25 (1.05 to 1.47) 0.009 1.17 (0.98 to 1.39) 0.082
XII L00 to L99 Diseases of the skin and subcutaneous tissue 155 (24.4) 1,918 (20.9) 1.22 (1.01 to 1.47) 0.036 1.27 (1.05 to 1.54) 0.016
XIII M00 to M99 Diseases of the musculoskeletal system and connective tissue 273 (43.1) 3,732 (40.7) 1.10 (0.93 to 1.29) 0.250 1.19 (1.01 to 1.41) 0.040
XIV N00 to N99 Diseases of the genitourinary system 233 (36.8) 2,984 (32.6) 1.20 (1.02 to 1.42) 0.030 1.24 (1.04 to 1.47) 0.015
XV O00 to O99 Pregnancy, childbirth and the puerperium 1 (0.2) 2 (0.0) – – – –
XVI P00 to P96 Certain conditions originating in the perinatal period 0 0 – – – –
XVII Q00 to Q99 Congenital malformations, deformations and chromosomal abnormalities 5 (0.8) 57 (0.6) 1.27 (0.51 to 3.18) 0.609 1.55 (0.61 to 3.98) 0.358
XVIII R00 to R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified 460 (72.6) 5,896 (64.4) 1.46 (1.22 to 1.75) <0.001 1.44 (1.19 to 1.73) <0.001
XIX S00 to T98 Injury, poisoning and certain other consequences of external causes 369 (58.2) 4,679 (51.1) 1.33 (1.13 to 1.57) 0.001 1.54 (1.30 to 1.83) <0.001
XX V01 to Y98 External causes of morbidity and mortality 0 1 (0.0) – – – –
XXI Z00 to Z99 Factors influencing health status and contact with health services 523 (82.5) 6,718 (73.3) 1.71 (1.39 to 2.11) <0.001 1.73 (1.39 to 2.16) <0.001
  1. Adjustment is made for age, sex, and Mini-Mental State Examination score. The AD group is considered the reference group. Statistically significant ORs (P < 0.05) in bold. AD, Alzheimer’s disease; CI, confidence interval; DLB, dementia with Lewy bodies; OR, odds ratio. aChi-square statistics. bBinary logistic regression model.
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Alzheimer's Research & Therapy

ISSN: 1758-9193