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Table 2 Comorbidity profile of the patients with dementia with Lewy bodies versus Alzheimer’s disease patients based on the chapters of the International Statistical Classification of Diseases and Related Health Problems, 10th Revision

From: Comorbidity profile in dementia with Lewy bodies versus Alzheimer’s disease: a linkage study between the Swedish Dementia Registry and the Swedish National Patient Registry

Chapter

Blocks

Title

DLB

AD

Unadjusted

Pvaluea

Adjusted

Pvalueb

(n=634)

(n=9,161)

OR (95%CI)

OR (95%CI)

I

A00 to B99

Certain infectious and parasitic diseases

87 (13.7)

1,064 (11.6)

1.21 (0.96 to 1.53)

0.111

1.25 (0.98 to 1.59)

0.069

II

C00 to D48

Neoplasms

203 (32.0)

2,733 (29.8)

1.11 (0.93 to 1.32)

0.245

1.06 (0.88 to 1.27)

0.541

III

D50 to D89

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

29 (4.6)

433 (4.7)

0.97 (0.66 to 1.42)

0.861

1.01 (0.68 to 1.49)

0.976

IV

E00 to E90

Endocrine, nutritional and metabolic diseases

79 (12.5)

1,088 (11.9)

1.06 (0.83 to 1.35)

0.661

1.16 (0.90 to 1.49)

0.239

V

F00 to F99

Mental and behavioral disorders

419 (66.1)

3,543 (38.7)

3.09 (2.61 to 3.66)

<0.001

3.14 (2.63 to 3.75)

<0.001

VI

G00 to G99

Diseases of the nervous system

558 (88.0)

6,508 (71.0)

2.99 (2.34 to 3.82)

<0.001

2.78 (2.15 to 3.58)

<0.001

VII

H00 to H59

Diseases of the eye and adnexa

367 (57.9)

4,390 (47.9)

1.49 (1.27 to 1.76)

<0.001

1.69 (1.42 to 2.01)

<0.001

VIII

H60 to H95

Diseases of the ear and mastoid process

96 (15.1)

1,462 (16.0)

0.94 (0.75 to 1.18)

0.586

0.97 (0.77 to 1.22)

0.810

IX

I00 to I99

Diseases of the circulatory system

293 (46.2)

3,693 (40.3)

1.27 (1.08 to 1.49)

0.003

1.29 (1.08 to 1.52)

0.004

X

J00 to J99

Diseases of the respiratory system

146 (23.0)

1,663 (18.2)

1.35 (1.11 to 1.63)

0.002

1.30 (1.06 to 1.59)

0.010

XI

K00 to K93

Diseases of the digestive system

237 (37.4)

2,966 (32.4)

1.25 (1.05 to 1.47)

0.009

1.17 (0.98 to 1.39)

0.082

XII

L00 to L99

Diseases of the skin and subcutaneous tissue

155 (24.4)

1,918 (20.9)

1.22 (1.01 to 1.47)

0.036

1.27 (1.05 to 1.54)

0.016

XIII

M00 to M99

Diseases of the musculoskeletal system and connective tissue

273 (43.1)

3,732 (40.7)

1.10 (0.93 to 1.29)

0.250

1.19 (1.01 to 1.41)

0.040

XIV

N00 to N99

Diseases of the genitourinary system

233 (36.8)

2,984 (32.6)

1.20 (1.02 to 1.42)

0.030

1.24 (1.04 to 1.47)

0.015

XV

O00 to O99

Pregnancy, childbirth and the puerperium

1 (0.2)

2 (0.0)

–

–

–

–

XVI

P00 to P96

Certain conditions originating in the perinatal period

0

0

–

–

–

–

XVII

Q00 to Q99

Congenital malformations, deformations and chromosomal abnormalities

5 (0.8)

57 (0.6)

1.27 (0.51 to 3.18)

0.609

1.55 (0.61 to 3.98)

0.358

XVIII

R00 to R99

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

460 (72.6)

5,896 (64.4)

1.46 (1.22 to 1.75)

<0.001

1.44 (1.19 to 1.73)

<0.001

XIX

S00 to T98

Injury, poisoning and certain other consequences of external causes

369 (58.2)

4,679 (51.1)

1.33 (1.13 to 1.57)

0.001

1.54 (1.30 to 1.83)

<0.001

XX

V01 to Y98

External causes of morbidity and mortality

0

1 (0.0)

–

–

–

–

XXI

Z00 to Z99

Factors influencing health status and contact with health services

523 (82.5)

6,718 (73.3)

1.71 (1.39 to 2.11)

<0.001

1.73 (1.39 to 2.16)

<0.001

  1. Adjustment is made for age, sex, and Mini-Mental State Examination score. The AD group is considered the reference group. Statistically significant ORs (P < 0.05) in bold. AD, Alzheimer’s disease; CI, confidence interval; DLB, dementia with Lewy bodies; OR, odds ratio. aChi-square statistics. bBinary logistic regression model.
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Alzheimer's Research & Therapy

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