|
Characteristic
|
Dementia with Lewy bodies
|
Alzheimer’s disease
|
Pvalue
|
|---|
|
(n=634)
|
(n=9,161)
|
|---|
|
Gender
| | |
<0.001
a
|
|
Female
|
252 (39.7%)
|
5973 (65.2%)
|
|
Male
|
382 (60.3%)
|
3188 (34.8%)
|
|
Age (years)
|
76.5 (7.1)
|
77.6 (8.3)
|
<0.001
b
|
|
MMSE score
|
21.4 (5.0)
|
21.5 (5.0)
|
0.593b
|
|
Body mass index (kg/m2)
|
24.4 (4.1)
|
24.3 (4.1)
|
0.565b
|
|
Living place
| | |
<0.001
a
|
|
Own house
|
559 (88.2%)
|
8627 (94.4%)
|
|
Nursing home
|
75 (11.8%)
|
512 (5.6%)
|
|
Co-resident
| | |
<0.001
a
|
|
Yes
|
218 (36.0%)
|
3879 (44.0%)
|
|
No
|
387 (64.0%)
|
4938 (56.0%)
|
|
Medication (at the time of diagnosis)
| | |
|
Cholinesterase inhibitors
|
465 (73.6%)
|
6598 (72.7%)
|
0.272a
|
|
NMDA antagonist
|
95 (15.0%)
|
895 (9.9%)
|
<0.001
a
|
|
Antidepressants
|
220 (34.8%)
|
2382 (26.3%)
|
<0.001
a
|
|
Antipsychotics
|
103 (16.3%)
|
447 (4.9%)
|
<0.001
a
|
|
Anxiolytics
|
84 (13.3%)
|
747 (8.2%)
|
<0.001
a
|
|
Hypnotics
|
106 (16.8%)
|
1292 (14.2%)
|
0.065a
|
|
Cardiovascular drugs
|
365 (57.8%)
|
4825 (53.2%)
|
0.054a
|
|
Total number of drugs
|
4.7 (3.0)
|
3.7 (2.9)
|
<0.001
b
|
- Data presented as number (%) or mean (standard deviation). Statistically significant differences (P≤0.05) in bold. MMSE, Mini-Mental State Examination; NMDA, N-methyl d-aspartate. aPearson chi-square statistic. bIndependent-sample t test.
