Age-related deficit accumulation and the risk of late-life dementia

Table 3 Odds ratios for death and dementia using the all-factor frailty index (age adjusted)

Outcome	B	SEM	Wald	Exp(B)	95%CI
Outcome	B	SEM	Wald	Exp(B)	Lower	Upper
Death (Men)
Age	0.18	.011	285.73	1.20	1.17	1.22
Frailty Index	0.20	.018	125.36	1.22	1.18	1.26
Constant	−13.63	.776	308.84	0.00
Death (Women)
Age	0.17	.008	442.26	1.19	1.17	1.21
Frailty Index	0.13	.011	131.79	1.14	1.11	1.16
Constant	−13.63	.604	509.15	0.00
Dementia (Men)
Age	0.19	.017	118.34	1.20	1.17	1.25
Frailty Index	0.17	.028	35.92	1.18	1.12	1.25
Constant	− 15.63	1.259	154.14	0.00
Dementia (Women)
Age	0.22	.013	281.86	1.25	1.22	1.28
Frailty Index	0.07	.016	19.31	1.08	1.04	1.11
Constant	− 18.43	.999	340.62	0.00

Note: Values of the index are presented by using the deficit count (for example, we multiplied the index by 42 for the all-factor measure), to evaluate the change in risk seen with each added deficit. As a worked example, for each increase in deficit accumulation, the risk of death increased by 22% in men, 14% in women; for dementia, for each increase in deficit accumulation, the risk of dementia increased by 18% in men and 8% in women for dementia. Significance level, P < 0.001 for age and Frailty Index in each model.

ISSN: 1758-9193