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Table 1 Participant characteristics and neuropsychological performance

From: Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an 11C altropane positron emission tomography study

  PD subjects DLB subjects HCS
n 19 10 17
Age (years) 70.1 ± 7.0 72.1 ± 6.2 73.9 ± 6.7
Gender (female/male) 7/12a 1/9b 10/7a
Education (years) 16.4 ± 3.2 16.4 ± 3.5 16.2 ± 2.9
l-Dopamine equivalent dose (mg) 476.2 ± 379.8c 256.0 ± 280.3 0d
Hoehn and Yahr stage 2.5 ± 0.4c 2.25 ± 1.1c 0e
Unified Parkinson Disease Rating Scale 20.9 ± 7.4 f 30.3 ± 2.9b 1.2 ± 2.5e
Duration of motor symptoms (years) 8.6 ± 5.1a 3.0 ± 0.7d -
Mini-Mental State Examination 28.1 ± 2.4a 19.3 ± 9.2b 28.9 ± 1.5a
Clinical Dementia Rating Scale - sum of boxes 0.4 ± 0.6a 7.2 ± 3.7b 0.1 ± 0.2a
Aggregate cognitive domain factors    
Executive    
Trailmaking Test B (seconds) 112.4 ± 67.7a 298.8 ± 3.0b 73.3 ± 27.7a
Digit Symbol 41.3 ± 9.0a 14.1 ± 11.1b 47.8 ± 21.6a
Episodic memory    
Logical Memory I 12.9 ± 5.4a 5.6 ± 1.5b 16.5 ± 3.8a
Logical Memory II 12.1 ± 6.0a 5.4 ± 4.9b 16.1 ± 4.1a
Semantic memory and language    
Free Selective Reminding Test 28.8 ± 6.0a 18.4 ± 10.0b 32.9 ± 6.2a
Free and Cued Selective Reminding Test 47.0 ± 1.6 45.3 ± 2.6 46.3 ± 4.0
Boston Naming Test 27.7 ± 1.7a 23.1 ± 7.9b 27.9 ± 3.0a
Letter Fluency 44.9 ± 12.4a 24.0 ± 14.1b 52.7 ± 12.2a
Category Fluency 31.8 ± 6.9a 13.9 ± 9.5b 38.9 ± 15.0a
Visuospatial skills    
Visual Form Discrimination Test 28.9 ± 3.5a 24.7 ± 5.0b 30.6 ± 2.4
  1. Values presented as mean ± standard deviation. PD, Parkinson disease without dementia; DLB, dementia with Lewy bodies; HCS, healthy control subjects. Significant differences (P<0.05) between groups are indicated as follows: adifferent from DLB; bdifferent from PD and HCS; cdifferent from HCS; ddifferent from PD; edifferent from PD and DLB; and fdifferent from DLB and HCS.