Figure 1

Pittsburgh Compound B retention in the brain. Pittsburgh Compound B (11C-PIB) retention in the brain of a healthy control (HC), an Alzheimer patient (AD), patients with mild cognitive impairment (MCI) who later at clinical follow-up converted to AD, and patients with MCI who did not later convert to AD. PIB+, high Pittsburgh Compound B retention; PIB-, low Pittsburgh Compound B retention. Red, high 11C-PIB retention; yellow, medium 11C-PIB retention; blue, low 11C-PIB retention.