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Table 2 Senile plaque and neurofibrillary tangle prevalence in the TASTY cohort by age group

From: CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques

Age group (years) Total Affected (%) P-value Odds Ratio 95% Confidence Interval
Senile plaques
   0 to 49 119 7 5.9 Ref - -
   50 to 59 101 17 16.8 0.013 3.24 1.29 to 8.16
   60 to 69 89 21 23.6 0.001 4.94 1.99 to 12.24
   70 to 79 130 56 43.1 <0.0001 12.11 5.23 to 28.01
   80+ 114 71 62.3 <0.0001 26.42 11.27 to 61.96
Neurofibrillary tangles
   0 to 49 103 13 12.6 Ref - -
   50 to 59 90 28 31.1 0.002 3.13 1.50 to 6.51
   60 to 69 82 23 28.0 0.010 2.70 1.27 to 5.74
   70 to 79 109 62 56.9 <0.0001 9.13 4.56 to 18.28
   80+ 100 78 78.0 <0.0001 24.55 11.60 to 51.95
  1. Those 'Affected' refers to those cases in the TASTY cohort that are affected by senile plaques or neurofibrillary tangles, accordingly.