Table 2 Senile plaque and neurofibrillary tangle prevalence in the TASTY cohort by age group
From: CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques
Age group (years) | Total | Affected (%) | P-value | Odds Ratio | 95% Confidence Interval | |
|---|---|---|---|---|---|---|
Senile plaques | ||||||
0 to 49 | 119 | 7 | 5.9 | Ref | - | - |
50 to 59 | 101 | 17 | 16.8 | 0.013 | 3.24 | 1.29 to 8.16 |
60 to 69 | 89 | 21 | 23.6 | 0.001 | 4.94 | 1.99 to 12.24 |
70 to 79 | 130 | 56 | 43.1 | <0.0001 | 12.11 | 5.23 to 28.01 |
80+ | 114 | 71 | 62.3 | <0.0001 | 26.42 | 11.27 to 61.96 |
Neurofibrillary tangles | ||||||
0 to 49 | 103 | 13 | 12.6 | Ref | - | - |
50 to 59 | 90 | 28 | 31.1 | 0.002 | 3.13 | 1.50 to 6.51 |
60 to 69 | 82 | 23 | 28.0 | 0.010 | 2.70 | 1.27 to 5.74 |
70 to 79 | 109 | 62 | 56.9 | <0.0001 | 9.13 | 4.56 to 18.28 |
80+ | 100 | 78 | 78.0 | <0.0001 | 24.55 | 11.60 to 51.95 |