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Table 6 Fixed effects of covariates including Aβ42/T-tau in the mixed model for NP-Batt (189 patients)

From: For debate: substituting placebo controls in long-term Alzheimer's prevention trials

Fixed effects

Value

Standard error

Degrees of freedom

t value

P value

Intercept

0.19832

0.09375

564

2.115

0.0348

Visit number

-0.07163

0.03346

564

-2.141

0.0327

Aβ42/T-tau

0.00328

0.01535

184

0.213

0.8312

FAQ at baseline

-0.01015

0.00508

184

-1.999

0.0472

ADAScog at baseline

0.00058

0.00463

184

0.125

0.9007

NP-Batt at baseline

0.99973

0.04373

184

22.861

<0.0001

Visit number × (Aβ42/T-tau)

0.02229

0.00548

564

4.065

0.0001

Visit number × ADAScog

-0.00398

0.00146

564

-2.719

0.0067

  1. Aβ42, β-amyloid1-42; ADAScog, Alzheimer Disease Assessment Scale - cognitive subscale; FAQ, Functional Assessment Questionnaire; NP-Batt, Neuro-Psychological Battery; T-tau, total tau protein.