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Table 6 Fixed effects of covariates including Aβ42/T-tau in the mixed model for NP-Batt (189 patients)

From: For debate: substituting placebo controls in long-term Alzheimer's prevention trials

Fixed effects Value Standard error Degrees of freedom t value P value
Intercept 0.19832 0.09375 564 2.115 0.0348
Visit number -0.07163 0.03346 564 -2.141 0.0327
Aβ42/T-tau 0.00328 0.01535 184 0.213 0.8312
FAQ at baseline -0.01015 0.00508 184 -1.999 0.0472
ADAScog at baseline 0.00058 0.00463 184 0.125 0.9007
NP-Batt at baseline 0.99973 0.04373 184 22.861 <0.0001
Visit number × (Aβ42/T-tau) 0.02229 0.00548 564 4.065 0.0001
Visit number × ADAScog -0.00398 0.00146 564 -2.719 0.0067
  1. Aβ42, β-amyloid1-42; ADAScog, Alzheimer Disease Assessment Scale - cognitive subscale; FAQ, Functional Assessment Questionnaire; NP-Batt, Neuro-Psychological Battery; T-tau, total tau protein.