Table 3 Fixed effects of the mixed model for the Neuro-Psychological Battery
From: For debate: substituting placebo controls in long-term Alzheimer's prevention trials
Fixed effects | Value | Standard error | Degrees of freedom | t value | P value |
|---|---|---|---|---|---|
Intercept | 0.92879 | 0.22683 | 1,065 | 4.095 | < 0.0001 |
BMI-2 (category 25 to 30 kg/m2) | -0.06911 | 0.03812 | 366 | -1.813 | 0.0706 |
BMI-3 (category >30 kg/m2) | -0.04498 | 0.05337 | 366 | -0.843 | 0.3999 |
Visit number | 0.01241 | 0.02184 | 1,065 | 0.568 | 0.5701 |
Apolipoprotein E4 | 0.03383 | 0.02608 | 366 | 1.298 | 0.1953 |
Age | -0.00887 | 0.00292 | 366 | -3.040 | 0.0025 |
FAQ at baseline | -0.11273 | 0.03835 | 366 | -2.939 | 0.0035 |
ADAScog at baseline | -0.00299 | 0.00339 | 366 | -0.882 | 0.3782 |
NP-Batt at baseline | 0.97529 | 0.03019 | 366 | 32.303 | <0.0001 |
(BMI-2) × Visit number | 0.02130 | 0.01366 | 1,065 | 1.559 | 0.1192 |
(BMI-3) × Visit number | 0.05513 | 0.02003 | 1,065 | 2.752 | 0.0060 |
Visit number × apolipoprotein E | -0.03558 | 0.00932 | 1,065 | -3.818 | 0.0001 |
Visit number × ADAScog | -0.00557 | 0.00104 | 1,065 | -5.374 | <0.0001 |
Age × FAQ | 0.00140 | 0.00051 | 366 | 2.723 | 0.0068 |