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Table 3 Fixed effects of the mixed model for the Neuro-Psychological Battery

From: For debate: substituting placebo controls in long-term Alzheimer's prevention trials

Fixed effects Value Standard error Degrees of freedom t value P value
Intercept 0.92879 0.22683 1,065 4.095 < 0.0001
BMI-2 (category 25 to 30 kg/m2) -0.06911 0.03812 366 -1.813 0.0706
BMI-3 (category >30 kg/m2) -0.04498 0.05337 366 -0.843 0.3999
Visit number 0.01241 0.02184 1,065 0.568 0.5701
Apolipoprotein E4 0.03383 0.02608 366 1.298 0.1953
Age -0.00887 0.00292 366 -3.040 0.0025
FAQ at baseline -0.11273 0.03835 366 -2.939 0.0035
ADAScog at baseline -0.00299 0.00339 366 -0.882 0.3782
NP-Batt at baseline 0.97529 0.03019 366 32.303 <0.0001
(BMI-2) × Visit number 0.02130 0.01366 1,065 1.559 0.1192
(BMI-3) × Visit number 0.05513 0.02003 1,065 2.752 0.0060
Visit number × apolipoprotein E -0.03558 0.00932 1,065 -3.818 0.0001
Visit number × ADAScog -0.00557 0.00104 1,065 -5.374 <0.0001
Age × FAQ 0.00140 0.00051 366 2.723 0.0068
  1. Standard deviation (residuals) = 0.2175. ADAScog, Alzheimer Disease Assessment Scale - cognitive subscale; BMI, body mass index; FAQ, Functional Assessment Questionnaire; NP-Batt, Neuro-Psychological Battery.