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Table 1 Demographic and baseline data for the mild cognitive impairment group

From: For debate: substituting placebo controls in long-term Alzheimer's prevention trials

Characteristic

Value

 

(n = 397)

Age (years)

74.2 (7.4)

Women

141 (36%)

Apolipoprotein E4

 

   0 E4 alleles

185 (47%)

   1 E4 allele

165 (42%)

   2 E4 alleles

47 (12%)

Education (years)

15. 7 (3.0)

Body mass index (kg/m2)

26.1 (4.0)

Hachinski modified (0 to 12)

1 (0 to 4)

FAQ (0 (normal) to 50)

2 (0 to 21)

MMSE (0 to 30 (best))

27.0 (1.8)

ADAScog, modified (0 (best) to 85)

18.6 (6.3)

NP-Batt (z score)

-1.02 (0.66)

Medication

240 (60%)

 

(n = 199)

β-amyloid1-42

146.9 (48.3 to 298.8)

Total tau protein

85.6 (28.5 to 463.2)

β-amyloid1-42/total tau protein

1.564 (0.233 to 7.61)

  1. Data presented as mean (standard deviation), n (%) or median (minimum to maximum). ADAScog, Alzheimer Disease Assessment Scale - cognitive subscale; FAQ, Functional Assessment Questionnaire; MMSE, Mini-Mental State Examination; NP-Batt, Neuro-Psychological Battery.