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Table 4 Joint consideration of β-amyloid and cognition for prediction of cognitive outcomes

From: Amyloid imaging and memory change for prediction of cognitive impairment

β-Amyloid Cognitively impaired/MCI CN with memory decline CN without memory decline
Positive Increased risk of ADa Increased risk of ADa Cognitive resilienceb or preclinical AD?
Negative Low risk of AD Low risk of AD Remain CN
  1. aSee Table 3 for review of rates of conversion. bMaintenance of cognitive health despite β-amyloid pathology. AD, Alzheimer's disease; CN, cognitively normal; MCI, mild cognitive impairment.