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Table 4 Joint consideration of β-amyloid and cognition for prediction of cognitive outcomes

From: Amyloid imaging and memory change for prediction of cognitive impairment

β-Amyloid

Cognitively impaired/MCI

CN with memory decline

CN without memory decline

Positive

Increased risk of ADa

Increased risk of ADa

Cognitive resilienceb or preclinical AD?

Negative

Low risk of AD

Low risk of AD

Remain CN

  1. aSee Table 3 for review of rates of conversion. bMaintenance of cognitive health despite β-amyloid pathology. AD, Alzheimer's disease; CN, cognitively normal; MCI, mild cognitive impairment.