Table 1 Different herbs and formulations effective in the treatment of Alzheimer's disease
From: Herbal therapy: a new pathway for the treatment of Alzheimer's disease
Product | Composition | Design | Outcome measure | Source |
|---|---|---|---|---|
Huperzine A | An extract from Lycopodium | A 12-week randomized, double-blind, placebo-controlled trial | ADAS-cog, MMSE, CIBIC-plus, ADL of patients with mild to moderate AD | Zhang and colleagues [7] |
Gingko Biloba | EGb 761 | A 24-week randomized, placebo- controlled, double-blind study | MMSE and CGI in patients with mild to moderate AD | Mazza and colleagues [4] |
Panax ginseng | Ginsenosides | A 12-week open-label, randomized double-blind, placebo-controlled study | ADAS and MMSE scores of AD patients | Lee and colleagues [17] |
Salvia officinalis | Leaf extract containing monoterpene, flavonoids, polyphenol | A 4-month, parallel-group, placebo- controlled trial | ADAS-cog and CDR in patients with mild to moderate AD | Akhondzadeh and colleagues [11] |
Ba Wei Di Hunag Wan | Powder of Rehmannia with another seven plants mixed with honey | An 8-week randomized, double-blind, placebo-controlled trial | MMSE and Barthel Index scores in patients with mild to severe dementia | Iwasaki and colleagues [15] |
Yi-Gan San formula | A mixture of seven different rootstock and branches, lyophilized dry extract | A 4-week randomized, observer-blind, controlled trial | NPI and ADL in patients with mild to severe dementia | Iwasaki and colleagues [16] |