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Table 4 Logistic regression model illustrating the odds of all-cause dementia (95% confidence intervals) by combinations of stroke and APOE genotype

From: Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study

  n Basic adjusted models* Fully adjusted models†
Stroke - APOE ε4 - 388 Reference Reference
Stroke + APOE ε4 - 219 2.2 (1.2-4.0) 2.2 (1.1-4.2)
Stroke - APOE ε4 + 151 1.4 (0.8-2.4) 1.3 (0.7-2.5)
Stroke + APOE ε4 + 84 14.8 (6.3-34.9) 14.9 (5.8-38.0)
P for stroke × APOE ε4 interaction = 0.001†    
  1. Population weights are used to adjust for the sampling design. *Adjusted for age, sex, education, ethnicity, and Health and Retirement Study (HRS) wave. †Adjusted for age, sex, education, ethnicity, HRS wave, heart disease, hypertension, and diabetes. APOE ε4, apolipoprotein ε4.