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Figure 1 | Alzheimer's Research & Therapy

Figure 1

From: Pro: Can biomarkers be gold standards in Alzheimer's disease?

Figure 1

Amyloid deposition in cognitively normal elders, mild cognitive impairment and Alzheimer's disease. (a) Representative 11C-PiB positron emission tomography images from a cognitively normal older individual (CN) without evidence of amyloid pathology (PiB-), from a normal older individual with elevated PiB retention indicating amyloid deposition (PiB+), and from a patient with mild Alzheimer's disease (AD) with extensive amyloid deposition. (b) Scatterplot of PiB distribution volume ratio (DVR) for CN, mild cognitive impairment (MCI) and AD groups, demonstrating a subset of CN and MCI individuals with evidence of amyloid deposition in the range of AD patients.

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