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Table 4 Whole brain atrophy rates for subjects treated with placebo or galantamine, stratified according to apolipoprotein E genotype

From: The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial

  Placebo Galantamine Adjusted mean difference 95% CI
APOE ϵ4 noncarriers 0.48 0.41 0.07 −0.10; 0.25
APOE ϵ4 carriers 0.77 0.49 0.28 0.07; 0.50
  1. Data presented as percentage change per year. The numbers of subjects per cell were as follows: APOE ϵ4 noncarriers, total n = 109 (placebo, n = 54; galantamine, n = 55), APOE ϵ4 carriers, total n = 97 (placebo, n = 54; galantamine, n = 43). APOE, apolipoprotein E; CI, confidence interval.