The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial

Table 3 Whole brain atrophy rates for subjects treated with placebo and with galantamine

	Placebo	Galantamine	Adjusted mean difference	95% CI
Whole brain atrophy rate	0.63	0.46	0.17	0.04 to 0.30
Hippocampal atrophy rate	1.70	1.94	−0.24	−0.62 to 0.12

Data presented as percentage change per year. The numbers of subjects per cell are as follows: whole brain atrophy rate, total n = 242 (placebo, n = 130; galantamine, n = 112); hippocampal atrophy rate, total n = 302 (placebo, n = 160; galantamine, n = 142). CI, confidence interval.