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# Table 1
**Population demography and biomarker values**

From: A diagnostic scale for Alzheimer’s disease based on cerebrospinal fluid biomarker profiles

Paris-1 | Paris-2 | Lille-1 | Lille-2 | Montpellier-1 | Montpellier-2 | RSB | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|

AD = 118
n | Mean | SD |
AD = 41
n | Mean | SD |
AD = 118
n | Mean | SD |
AD = 73
n | Mean | SD |
AD = 129
n | Mean | SD |
AD = 142
n | Mean | SD |
AD = 213
n | Mean | SD |

Age | 73.6 | 8.8 | Age | 70.9 | 8.9 | Age | 68.3 | 9 | Age | 67 | 9.5 | Age | 69.7 | 8.8 | Age | 71.1 | 10.1 | Age | 66.3 | 8.7 |

Aβ42 | 440 | 189 | Aβ42 | 594 | 238 | Aβ42 | 338 | 162 | Aβ42 | 603 | 245 | Aβ42 | 505 | 224 | Aβ42 | 654 | 256 | Aβ42 | 420 | 224 |

Tau | 598 | 295 | Tau | 543 | 279 | Tau | 608 | 336 | Tau | 778 | 364 | Tau | 611 | 327 | Tau | 702 | 727 | Tau | 666 | 407 |

p-tau | 99 | 40.4 | p-tau | 86 | 34 | p-tau | 98.1 | 46.9 | p-tau | 101.5 | 41.2 | p-tau | 85.9 | 40.2 | p-tau | 86 | 37.7 | p-tau | 92.4 | 38.1 |

MMSE | 19.4 | 5.6 | MMSE | 18.7 | 6.7 | MMSE | 18.1 | 6.5 | MMSE | 19.6 | 6.3 | MMSE | 21.9 | 5.5 | MMSE | 20.7 | 7.4 | MMSE | 19.0 | 6.1 |

Sex (%M) | 47% | sex (%M) | 65% | sex (%M) | 37% | sex (%M) | 47% | sex (%M) | 47% | sex (%M) | 49% | sex (%M) | 50% | |||||||

NAD n = 53
| Mean | SD |
NAD n = 68
| Mean | SD |
NAD n = 128
| Mean | SD |
NAD n = 51
| Mean | SD |
NAD n = 215
| Mean | SD |
NAD n = 147
| Mean | SD |
NAD n = 195
| Mean | SD |

Age | 62.1 | 13.1 | Age | 67.4 | 11.1 | Age | 67.3 | 10.7 | Age | 64.6 | 10.7 | Age | 64.1 | 13.6 | Age | 63.4 | 13.6 | Age | 65.4 | 10.1 |

Aβ42 | 686 | 243 | Aβ42 | 843 | 246 | Aβ42 | 494 | 192 | Aβ42 | 974 | 355 | Aβ42 | 706 | 266 | Aβ42 | 999 | 373 | Aβ42 | 723 | 346 |

Tau | 253 | 226 | Tau | 223 | 141 | Tau | 273 | 197 | Tau | 284 | 149 | Tau | 291 | 233 | Tau | 310 | 241 | Tau | 339 | 258 |

p-tau | 48.6 | 23.1 | p-tau | 43.5 | 19.3 | p-tau | 52.6 | 28.7 | p-tau | 46.5 | 15.8 | p-tau | 44.8 | 23.7 | p-tau | 38.4 | 18.6 | p-tau | 49.3 | 25.8 |

MMSE | 23 | 5.3 | MMSE | 23.6 | 4.9 | MMSE | 21.3 | 5.5 | MMSE | 21. 2 | 6 | MMSE | 20.7 | 7.1 | MMSE | 21.1 | 6.9 | MMSE | 21.0 | 6.1 |

Sex (%M) | 53% | Sex (%M) | 49% | sex (%M) | 51% | sex (%M) | 59% | sex (%M) | 53% | sex (%M) | 55% | sex (%M) | 51% |