| |
CV medication (n= 13,847)
|
Without CV medication (n= 5,896)
|
P value
|
|---|
|
Age
| | | |
|
Mean
|
79.6 ± 7.2
|
77.4 ± 8.9
|
<0.001
|
|
Range
|
33 to 103
|
27 to 97
|
|
Gender
| | | |
|
Female (%)
|
55.9
|
64.4
|
<0.001
|
|
Male (%)
|
44.1
|
35.6
|
|
MMSE
| | | |
|
Mean
|
21.4 ± 4.9
|
21.3 ± 5.2
|
<0.001
|
|
Range
|
0 to 30
|
0 to 30
|
|
Living alone (%)
|
43.7
|
45.7
|
0.006
|
|
ChEIs (%)
|
46.1
|
58.5
|
<0.001
|
|
NMDA antagonists (%)
|
10.6
|
10.3
|
0.028
|
|
Number of drugs
| | | |
|
Mean
|
5.8 ± 3
|
3,0 ± 2.5
|
<0.001
|
|
Range
|
0 to 24
|
0 to 21
|
|
AD (%)
|
34.9
|
56.0
|
<0.001
|
|
MixD (%)
|
28.9
|
20.4
|
<0.001
|
|
VaD (%)
|
30.3
|
13.2
|
<0.001
|
|
DLB (%)
|
2.6
|
4.2
|
<0.001
|
|
FTD (%)
|
1.6
|
3.2
|
<0.001
|
|
PDD (%)
|
1.7
|
2.9
|
<0.001
|
- AD, Alzheimer’s disease; ChEI, cholinesterase inhibitor; CV, cardiovascular; DLB, dementia with Lewy bodies; FTD, frontotemporal dementia; MixD, mixed dementia; MMSE, Mini Mental State Examination; NMDA, N-methyl-d-aspartate; PDD, Parkinson’s disease dementia; VaD, vascular dementia.
