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Figure 1 | Alzheimer's Research & Therapy

Figure 1

From: Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson’s disease with dementia and dementia with Lewy bodies compared to Alzheimer’s disease

Figure 1

Levels of α-synuclein oligomers (A; RLU, relative luminescence units) and the ratio of α-synuclein oligomers to total-α-synuclein (B; oligomer/total ratio, %) in the CSF of healthy elderly individuals ( n= 98) and of patients with PDD ( n= 30), DLB (n = 71) or AD ( n= 48). The levels of α-synuclein oligomers and the ratio were increased in patients with PDD compared with patients with AD and healthy controls (Mann–Whitney U test; P < 0.05). The box represents the interquartile range (IQR), with the median indicated in the middle. The error bars represent the lowest and highest normal values (max 1.5 box lengths from the lower and upper quartiles, respectively).

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