Table 1 Demographics, cognitive test scores and CSF biomarker levels for the five genotypes (means with SD)
ApoE Genotype | n | Age Years | MMSE | ADAS-Cog | Picture recognition-pattern separation task | Power of attention | Aβ42 | P-tau | T-tau | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Difficult separations | Easy separations | msec | ||||||||||
% Correct | Speed | % Correct | Speed | |||||||||
∈2/∈3 | 5 | 77 (10) | 22 (5) | 15 (8) | 70 (28) | 2,981 (3,137) | 81 (15) | 1,384 (443) | 1,555 (296) | 715 (113) | 63 (17) | 457 (147) |
∈3/∈3 | 10 | 75 (9) | 23 (4) | 15 (10) | 77 (26) | 2,393 (1,450) | 81 (17) | 1,774 (1639) | 1,621 (596) | 536 (316) | 76 (27) | 555 (214) |
∈4/∈2 | 2 | 75 (10) | 26 (1) | 9 (1) | 79 (0) | 1,078 (280) | 86 (10) | 1,099 (262) | 1,430 (326) | 439 (256) | 66 (35) | 535 (274) |
∈4/∈3 | 28 | 76 (6) | 25 (4) | 13 (7) | 82 (21) | 1,830 (1,197) | 82 (24) | 1,483 (972) | 1,504 (459) | 414 (179) | 99 (45) | 748 (395) |
∈4/∈4 | 5 | 70 (6) | 22 (3) | 19 (3) | 44 (24) | 4,263 (5,567) | 84 (11) | 2,132 (1,621) | 1,579 (457) | 295 (60) | 97 (12) | 769 (146) |