Table 2 Selected patient characteristics at baseline by preprogression category (n = 597)
Variable | Mean ± SD or n (Percent) | |||
|---|---|---|---|---|
| Â | Fast (N = 124) | Intermediate (n = 274) | Slow (n = 199) | P * |
Age at Diagnosis (years) | 74.0 ± 8.7 | 73.6 ± 8.8 | 72.9 ± 8.2 | .516 |
Sex (% female) | 72.6 | 68.3 | 58.3 | .016 |
Race/Ethnic Group (% white) | 90.3 | 91.2 | 90.9 | .957 |
Years of Education | 13.0 ± 3.1 | 13.7 ± 3.1 | 14.4 ± 3.4 | <.001 |
Estimated duration of disease before diagnosis (yrs) | 1.7 ± 0.9 | 3.4 ± 1.6 | 4.9 ± 2.6 | <.001 |
Baseline MMSE | 18.1 ± 5.0 | 20.3 ± 4.4 | 24.7 ± 3.8 | <.001 |
First AMNART (estimated IQ) | 105.5 ± 9.8 | 106.3 ± 10.2 | 110.7 ± 9.6 | <.001 |
Baseline MMSE | 18.1 ± 5.0 | 20.3 ± 4.4 | 24.7 ± 3.8 | <.001 |
Hallucinations (% yes at or before Baseline) | 21.0 | 21.9 | 12.6 | .027 |
Delusions (% yes at or before Baseline) | 40.32 | 46.0 | 34.2 | .035 |
Parkinsonian Symptoms at Baseline | 6.5 | 4.4 | 3.0 | .147 |
Number of APOE ε4 Alleles (% in each group) |  |  |  |  |
   0 | 22.2 | 47.3 | 30.6 | .573 |
   1 | 19.4 | 46.2 | 34.4 |  |
   2 | 20.0 | 40.0 | 40.0 |  |
ADAS Cog | 27.4 ± 12.0 | 24.9 ± 11.0 | 17.6 ± 8.4 | <.001 |
CDR Sum of Boxes | 6.7 ± 3.9 | 6.0 ± 3.6 | 4.0 ± 2.8 | <.001 |
PSMS | 7.7 ± 2.5 | 7.7 ± 2.7 | 7.2 ± 2.2 | .177 |
IADL | 16.0 ± 6.8 | 15.2 ± 6.3 | 13.3 ± 5.5 | .002 |
VSAT (time) | 250.2 ± 91.6 | 229.15 ± 87.6 | 184.6 ± 73.7 | <.001 |
VSAT (errors) | 18.3 ± 11.8 | 15.0 ± 9.9 | 9.5 ± 8.1 | <.001 |