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Table 2 Selected patient characteristics at baseline by preprogression category (n = 597)

From: Predicting progression of Alzheimer's disease

Variable Mean ± SD or n (Percent)
  Fast
(N = 124)
Intermediate
(n = 274)
Slow
(n = 199)
P *
Age at Diagnosis (years) 74.0 ± 8.7 73.6 ± 8.8 72.9 ± 8.2 .516
Sex (% female) 72.6 68.3 58.3 .016
Race/Ethnic Group (% white) 90.3 91.2 90.9 .957
Years of Education 13.0 ± 3.1 13.7 ± 3.1 14.4 ± 3.4 <.001
Estimated duration of disease before diagnosis (yrs) 1.7 ± 0.9 3.4 ± 1.6 4.9 ± 2.6 <.001
Baseline MMSE 18.1 ± 5.0 20.3 ± 4.4 24.7 ± 3.8 <.001
First AMNART (estimated IQ) 105.5 ± 9.8 106.3 ± 10.2 110.7 ± 9.6 <.001
Baseline MMSE 18.1 ± 5.0 20.3 ± 4.4 24.7 ± 3.8 <.001
Hallucinations (% yes at or before Baseline) 21.0 21.9 12.6 .027
Delusions (% yes at or before Baseline) 40.32 46.0 34.2 .035
Parkinsonian Symptoms at Baseline 6.5 4.4 3.0 .147
Number of APOE ε4 Alleles (% in each group)     
   0 22.2 47.3 30.6 .573
   1 19.4 46.2 34.4  
   2 20.0 40.0 40.0  
ADAS Cog 27.4 ± 12.0 24.9 ± 11.0 17.6 ± 8.4 <.001
CDR Sum of Boxes 6.7 ± 3.9 6.0 ± 3.6 4.0 ± 2.8 <.001
PSMS 7.7 ± 2.5 7.7 ± 2.7 7.2 ± 2.2 .177
IADL 16.0 ± 6.8 15.2 ± 6.3 13.3 ± 5.5 .002
VSAT (time) 250.2 ± 91.6 229.15 ± 87.6 184.6 ± 73.7 <.001
VSAT (errors) 18.3 ± 11.8 15.0 ± 9.9 9.5 ± 8.1 <.001
  1. *P-values based on one-way analysis of variance for continuous variables or Chi square test for categorical variables
  2. ADAS-cog = Alzheimer's disease Assessment Scale-cognitive subscale; AMNART = American version of the New Adult Reading Test; CDR = Clinical Dementia Rating Scale; IADL = Instrumental Activities of Daily Living scale; MMSE = Mini Mental Status Exam; PSMS = Physical Self-Maintenance Scale; VSAT = Verbal Series Attention Test