From: Platelet-activating factor antagonists enhance intracellular degradation of amyloid-β42 in neurons via regulation of cholesterol ester hydrolases
Concentration of Aβ42, nM
Cell extracts
DRMs
Lysosomes
Control
8.7 ± 0.7
8.4 ± 0.6
0.4 ± 0.2
DEUP
8.6 ± 0.9
2.2 ± 0.7a
2.8 ± 0.3b
Squalene
8.5 ± 0.9
8 ± 0.4
0.5 ± 0.2
DEUP + squalene
8.9 ± 0.8
2 ± 0.6a
2.7 ± 0.3b