Table 2 Concentration of flurbiprofen in the abluminal compartment measured by HPLC
From: Nanoparticulate flurbiprofen reduces amyloid-β42 generation in an in vitro blood–brain barrier model
μM luminally administered | μM abluminally measured by HPLC | % of administered concentration |
|---|---|---|
300 μM flurbiprofen | 41.85 | 13.95 |
300 μM PLA-flurbiprofen nanoparticles | 31.56 | 10.52 |
450 μM PLA-flurbiprofen nanoparticles | 46.82 | 10.40 |
600 μM PLA-flurbiprofen nanoparticles | 63.95 | 10.66 |
750 μM PLA-flurbiprofen nanoparticles | 83.70 | 11.16 |