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Figure 5 | Alzheimer's Research & Therapy

Figure 5

From: Early-onset dementias: diagnostic and etiological considerations

Figure 5

Contrasting atrophy patterns for behavioral variant frontotemporal dementia and early-onset familial Alzheimer's disease. Axial T1 magnetic resonance imaging contrasting atrophy patterns for (a) a patient with behavioral variant frontotemporal dementia due to progranulin (GRN) mutation and (b) a patient with early-onset familial Alzheimer's disease due to presenilin (PS1) mutation. (a) Striking asymmetry in frontotemporal and parietal lobes associated with GRN mutations. (b) More mesiotemporal and posterior predilection associated with PS1 mutations.

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