Figure 4
From: Early-onset dementias: diagnostic and etiological considerations
Diagnostic algorithm for investigating patients having confirmed episodic memory deficits. *PET/SPECT, fluorodeoxyglucose positron emission tomography and perfusion single photon emission computed tomography. **Only available in Canada through research studies. See Figure 6 for flowchart 2. A-β, amyloid beta; AD, Alzheimer's disease; APP, amyloid precursor protein; CSF, cerebrospinal fluid; EEG, electroencephalogram; FLAIR, fluid-attenuated inversion recovery; HSV, herpes simplex virus; MRI, magnetic resonance imaging; PCR, polymerase chain reaction; PLEDS, periodic lateralized epileptiform discharges; PS, presenilin; SORL1, sortilin-related receptor LR11/SorLA.