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Figure 2 | Alzheimer's Research & Therapy

Figure 2

From: Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

Figure 2

Anxiety-related behavior of APP/PS1 KI and wild-type control mice. (A) No difference in the time spent exploring in the center zone between the amyloid precursor protein/presenilin-1 knock-in (APP/PS1 KI) mice and the wild-type (WT) mice was observed in any age group. (B) Elevated plus maze anxiety behavior is also similar between APP/PS1 KI and WT mice for all ages. Number of mice: 10 WT and nine KI mice aged 7 months; five WT and eight KI mice aged 11 months; eight WT and eight KI mice aged 15 months; and eight WT and five KI mice aged 24 months.

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