Modeling the heterogeneity in risk of progression to Alzheimer's disease acrosscognitive profiles in mild cognitive impairment

Table 6 Multivariate logistic regression model with outcome as conversion toAlzheimer's disease (AD) from mild cognitive impairment (MCI) within 24 monthsfrom baseline

Explanatory variables	B	Wald test P-value	Exp (B)
APOE4	0.623	0.024	0.536
Episodic memory level 2	-1.445	0.001	0.236
Perceptual motor speed	-0.926	0.009	0.396
Intercept	1.193	0.000	3.298

Dependent variable value of 1 indicates that a subject has converted to AD fromMCI within 24 months of baseline. Binary variable Apolipoprotein (APOE)4 = 1indicates that the subject has at least one APOE4 allele and higher risk forconversion. Larger probability values of relatively high performance indicatelower risk for conversion.

ISSN: 1758-9193