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Table 3 Demographic, cognitive and neuroimaging data in the high and low 18F-florbetaben retention groups

From: 18F-florbetaben Aβ imaging in mild cognitive impairment

 

All MCI (n= 45)

 

Low Aβ (SUVR < 1.45)

High Aβ (SUVR ≥ 1.45)

Number (% of total)

21 (47)

24 (53)

Age

71.8 ± 6.1

73.5 ± 6.9

Years of education

13.5 ± 3.0

13.8 ± 4.2

MMSE

27.9 ± 1.4

26.7 ± 1.9*

CDR

0.4 ± 0.2

0.5 ± 0.0*

CDR SOB

1.3 ± 0.9

1.6 ± 1.0

Composite EM

-1.4 ± 0.8

-2.8 ± 1.0*

Composite NM

-1.0 ± 0.9

-0.8 ± 0.8

Neocortical SUVR

1.30 ± 0.09

1.75 ± 0.19*

Hippocampal volume (cm3)

7.4 ± 1.1

6.9 ± 0.8

WMH volume (cm3)

9.9 ± 10.2

10.5 ± 11.8

  1. Aβ, β-amyloid; CDR, Clinical Dementia Rating; EM, episodic memory z score; MCI, mild cognitive impairment; NM, nonmemory z score; SOB, sum of boxes, SUVR, standard uptake value ratio; WMH, white matter hyperintensities. *P < 0.05.