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Figure 3 | Alzheimer's Research & Therapy

Figure 3

From: Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome

Figure 3

Posterior cortical atrophy (PCA). A 67 year old man presenting with mild memory loss and striking visuospatial difficulties, later developing parkinsonism. Imaging 6 years into the disease course, including axial T1 MRI at the level of the midbrain (top left) and basal ganglia (bottom left), demonstrated temporal-occipital atrophy, posterior atrophy and ventricular expansion (white arrows), slightly greater on the right. Axial single-photon emission computed tomography (SPECT) imaging done at the same time (right) demonstrated bilateral posterior hypoperfusion (red arrows), greater on the right. The patient died 7 years into the course of disease, and autopsy revealed Alzheimer's disease (Braak IV/VI) with co-occurring Lewy bodies (Braak VI/VI).

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