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Table 1 Compartment parameters.

From: Simulations of symptomatic treatments for Alzheimer's disease: computational analysis of pathology and mechanisms of drug action

Compartment

Length, μ m

Diameter, μ m

gNaf

gNap

gHva

gKdr

gKs

gCa

Pyr - Apical-distal

400.0

2.6

0.028

0

0.000255

0.0092

0.00018

0.0022

Pyr- Proximal-distal

400.0

2.6

0.028

0.001

0.00063

0.0092

0.00018

0.0038

Pyr - Basal

150.0

16.0

0.028

0.001

0.00063

0.0092

0.00018

0.0038

Pyr - Soma

86.3

6.14

0.086

0.0022

0.000306

0.0338

0.000105

0.0022

Int - Dendrite

150.0

10.0

0.02

-

-

0.008

-

-

Int - Soma

15.0

15.0

0.1

-

-

0.04

-

-

  1. Parameters adapted from [11] for dimensions and current densities of the model compartments.