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Figure 6 | Alzheimer's Research & Therapy

Figure 6

From: Simulations of symptomatic treatments for Alzheimer's disease: computational analysis of pathology and mechanisms of drug action

Figure 6

Figure 6 Global correlation between Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-Cog) outcomes and model predictions. Global linear correlation between reported ADAS-Cog outcomes from 28 different therapeutic interventions and their corresponding working memory effects in the computer model of Alzheimer's disease (P < 0.0001). Because ADAS-Cog readouts monitor errors, positive values are associated with shorter working memory spans and worse performance.

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