Skip to main content

Table 1 Demographic characteristics of the cohort of 172 sequenced samples

From: Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort

Demographic characteristics   
Age at onset of AD Years  
   Mean 59.56  
   Standard deviation 8.19  
   Range 29.5-87.5  
  Number Percentage
Diagnosis   
   Familial early-onset AD (onset ≤65 years) 15 8.98%
   Sporadic early-onset AD (onset ≤65 years) 136 81.44%
   Familial late-onset AD (onset >65 years) 16 9.58%
   Clinical AD 167 97.09%
   Autopsy-confirmed 5 2.91%
APOE   
   ε2ε2+ε2ε3 3 1.75%
   ε3ε3 79 45.93%
   ε3ε4 66 38.37%
   ε4ε4 24 13.95%
Birth country   
   Spain 161 93.60%
   Uruguay 11 6.40%
Gender   
   Male 62 36.05%
   Female 105 61.05%
   Unknown 5 2.91%
  1. AD, Alzheimer's disease; APOE, apolipoprotein E.