From: Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains
Aβ Peptide | predicted MW | observed MW | AD (n= 16) | PA (n= 9) | NDC (n= 8) |
---|---|---|---|---|---|
1-18 | 2167.28 | 2167.70 | 2 (12.5%) | ||
1-26 | 3020.16 | 3021.02 | 2 (25%) | ||
pE11-40 | 3115.65 | 3151.47 | 1 (12.5%) | ||
1-27 | 3134.27 | 3134.77 | 1 (12.5%) | ||
pE11-42 | 3317.90 | 3318.91 | 1 (6.3%) | 2 (22.2%) | |
9-40 | 3371.90 | 3372.97 | 8 (50%) | 6 (66.7%) | 5 (62.5%) |
1-30 +16 Da | 3406.57 | 3409.22 | 1 (6.3%) | ||
1-36 | 4017.42 | 4019.60 | 1 (6.3%) | ||
1-37 | 4074.47 | 4076.58 | 2 (12.5%) | ||
1-37 +16 Da | 4090.47 | 4094.07 | 1 (6.3%) | ||
1-38 | 4131.52 | 4134.52 | 4 (25.0%) | ||
1-38 + 16 Da | 4147.52 | 4150.11 | 1 (6.3%) | ||
4-42 | 4198.74 | 4200.32 | 2 (22.2%) | ||
4-42 +16 Da | 4214.74 | 4216.78 | 1 (6.3%) | 1 (11.1%) | 1 (12.5%) |
1-39 | 4230.65 | 4232.14 | 2 (12.5%) | 1 (11.1%) | |
3-41 | 4256.85 | 4260.60 | 2 (12.5%) | 1 (11.1%) | |
pE3-42 | 4309.90 | 4312.76 | 1 (11.1%) | ||
1-40 | 4329.78 | 4332.14 | 12 (75.0%) | 6 (66.7%) | 2 (25%) |
1-40 +16 Da | 4345.78 | 4347.41 | 7 (43.8%) | 1 (11.1%) | 1 (12.5%) |
2-42 | 4395.93 | 4399.63 | 1 (12.5%) | ||
1-41 | 4442.94 | 4444.51 | 1 (6.3%) | 1 (11.1%) | |
1-42 | 4514.02 | 4516.58 | 16 (100%) | 9 (100%) | 4 (50%) |
1-42 +16 Da | 4530.02 | 4532.13 | 9 (56.3%) | 4 (44.4%) | 1 (12.5%) |
1-43 | 4615.20 | 4617.58 | 4 (25.0%) | 3 (33.3%) | 1 (12.5%) |