Figure 2
From: Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains
Immunohistochemical characterization of Aβ1-40 and Aβ1-42 in Alzheimer's disease (AD), pathological aging (PA) and normal non-demented controls (NDC). A-E. Representative paraffin embedded formalin fixed hippocampi from human AD (A, B), PA (C, D) and control (NDC; E) subjects were stained with 13.1.1 antibody (Aβ35-40). Insets show higher magnification with special emphasis on cored Aβ plaques associated with blood vessels in subjects with a post-mortem clinical pathological diagnosis of cerebral amyloid angiopathy (CAA+). Scale Bar, 600 μm (A-E), insets 60 μm (A-E). F-J. Representative paraffin embedded formalin fixed hippocampi from human AD (A, B), PA (C, D) and control (NDC; E) subjects were stained with 2.1.3 antibody (Aβ35-42). Insets show higher magnification with special emphasis on cored Aβ plaques associated with blood vessels in subjects with a post-mortem clinical pathological diagnosis of cerebral amyloid angiopathy (CAA+). Scale Bar, 600 μm (A-E), insets 60 μm (A-E). Aβ, amyloid β.