Skip to main content
Figure 6 | Alzheimer's Research & Therapy

Figure 6

From: Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice

Figure 6

Aβ ELISA assay of whole brain homogenates show no differences in Aβ levels by genotype. Aβ levels in 8-, 9-, 15- and 16 to 18-month-old with normal LRP1 levels (APPswe/PS1dE9(+)/LRP1lox/lox) were compared to those with lower LRP1 levels (GFAP-Cre +). There was no difference in Aβ levels by genotype by age (p values range 0.40 to 0.90 based on Student's t-test). ELISA data used to generate the graph are shown in Table 1, which includes information on the number of animals used at each age.

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193